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DNP (2,4-Dinitrophenol), an industrial chemical with various applications, has gained steady popularity as a fat loss tool. Boasting an astounding 50% increase in metabolic rate, it is able to contribute to reported fat losses of 10-12 pounds in 8 days of use. Classified as an “uncoupler of oxidative phosphorylation” medically, it is quite dangerous as there is no negative feedback system that may deal with overdoses. Specifically, there is no upper limit to the increase in body temperature that may be obtained with its use.
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IUPAC Name: 2,4-dinitrophenol
Molecular formula: C6H4N2O5
Molar mass: 184,106
Density: 1.683 g / cm³
Melting point: 108 ° C, 381 K, 226 ° F
Boiling point: 113 ° C, 386 K, 235 ° F
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For the purposes of this article, we will limit ourselves to the physiological application of DNP. If I had to describe DNP in one word poison. DNP prevents normal chemical reactions at the cellular level. It prevents the normal functioning of cellular metabolism. DNP fertilizer
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DNP makes changes in our metabolism. Metabolism is the set of chemical reactions in our body that keep us alive. Our body metabolises nutrients to provide us with energy. Oxidation involves the transfer of electrons between atoms (or molecules) and releases energy. The formal name for this process is oxidative phosphorylation. When our bodies break down nutrients and absorb them into our cells, one of the functions of the cells’ mitochondria is to produce chemical energy called ATP. To create ATP, mitochondria capture and use the energy released by oxidative phosphorylation. DNP G fertilizer Price
DNP is known as a mitochondrial uncoupler of oxidative phosphorylation. In other words, DNP encapsulates and moves protons (ions) across cell membranes, preventing mitochondria from “processing” nutrient molecules by capturing energy through electron exchange and converting this energy into ATP. The energy released by the action of DNP is converted into thermal energy. Without ATP to provide energy, our bodies look for alternative sources, such as fat stores. The overall result is an increase in metabolic rate by a factor of 30% to 50%.
What is DNP?
One might wonder why the body doesn’t use muscle and fat for energy (catabolism). One of the reasons is in the HSPs (heat shock proteins). HSPs are known to maintain the shape and function of cellular proteins and promote muscle growth. HSPs work in circumstances where body temperature increases, ATP is low and free radicals are present. DNP does all of these things. Although some catabolism is likely to occur with the presence of DNP, it follows that exercise combined with HSP release results in the protection of muscle cells and the promotion of protein synthesis. DNP Fertilizer content
How dangerous is DNP?
DNP can kill you. We discussed how DNP converts dietary energy into heat energy, which increases body temperature. Unfortunately, there is no limit to how high your body temperature can get while taking DNP, so you can literally “roast” it.
DNP can cause fever, stroke, nephritis, tachycardia, breathing problems, coma and peripheral neuritis.
DNP is a cumulative poison, which means it builds up in your system every day you take it. It takes 3 weeks to clear your system and by the time you have a problem, it may be too late. DNP Organic fertilizer
DNP causes cataracts in 1 in 1,000 people.
10% of users develop an allergic reaction that includes hives, blisters and rashes.
Without ATP, cells begin to die.
Free radicals cause cancer.
The EPA, NTP, ASTDR and WHO classify DNP as a category 1 toxic chemical.
We really don’t know how much cellular damage DNP causes.
What are the benefits of DNP?
Anabolic recovery: after a DNP cycle, the body is in a highly anabolic state.
T3 reduction: if you are running DNP immediately after an AAS
cycle, DNP can reduce the overproduction of T3 that causes much of the
Catabolic muscle loss after the cycle.
Note: DNP can reduce T3 to less than optimal levels, so in some cases you may need to start small doses of T3.
How should I take DNP?
I take a conservative stance on when to use DNP, how much to use, and for how long. DNP fertilizer capsules
Some people argue that DNP should be use in the cycle to protect the muscle. My opinion is that DNP makes you feel like shit and can impair weight lifting while cycling. If I’m on the bike, I want to lift a lot of weight and don’t want to worry about sunstroke or energy levels. Dnp fertilizer price
Other people argue that DNP should be used long after the PCT. My only concern would be low energy levels and possible T3 issues. These concerns can be managed through things like ECA stacks and T3 integration.
My favorite time to do DNP is when I start the PCT. I still have energy and strength from my cycle and avoid the whole post-cycle catabolic phase. Plus, I have a little anabolic recovery at the end of my DNP career and can see the results of all my hard work on the team.
DNP is cumulative and takes three weeks to clear your system. Don’t increase the dose because you think you can take more. Don’t use drugs or drink alcohol.
Note that you do not have to “listen” to DNP for it to work. People have different tolerance levels, even to poisons. You can only get a limited amount of DNP into your system (before you die), so you can choose to do a higher dose short cycle or a lower dose long cycle. Regardless, the heat and toxicity will be felt at the end of the cycle.
Long low dose cycle
Start with a dose of 200 mg per day [100 mg every morning / 100 mg
Each evening]. Run it for two to three weeks.
Day 1 – 14: 200 mg ED
Day 15-21: 200 mg ED
* Advanced users may choose to cycle for an additional week.
Total DNP consumption for the long cycle: (2,800 to 4,200 mg)
Short cycle high dose
Start with a dose of 200 mg per day [100 mg every morning / 100 mg
Each evening]. Within 2 to 4 days, you should know if you are allergic.
1 – 4: 200 mg ED
5 – 9: 400 mg ED
10-11: 400 mg ED *
* Experienced users may choose to go beyond the maximum recommended daily dose of 400 mg.
and run the cycle for a few more days.
Total DNP consumption for short cycle: (2,800 to 4,000 mg)
What are the common side effects of DNP?
Malaise and sweating
Yellow body fluids
Cravings for carbohydrates
Vomiting (a good sign to stop)
What foods and supplements should I take during a DNP cycle?
You may lose your sense of taste and smell, so this is a great time to learn to eat without using spices and all the other things you don’t need. Buy DNP capsules online
Water: one or two litres a day. Dehydration is the main cause of DNP problems, including death.
Fruit: glycogen will be depleted. Fructose is good.
Protein: diet should be high in protein.
Fibre – DNP can be difficult, so you may want to adjust it (pun intended).
Complex carbohydrates – carbohydrates will keep you warm. You should try to schedule your carbohydrate intake so that you don’t eat carbs before workouts or before bed.
Multivitamins – you are probably on a restrictive diet and need a supplement.
Antioxidants: to stop free radicals.
Electrolytes – V8 is good.
Melatonin: if needed, to help you sleep.
ECA battery: if needed to increase your energy levels.
7 day DNP cycles:
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the first 3 days: 200 mg per day;
next 4 days: 400 mg per day (which means you need to take 400 mg for 4 days).
2,4-Dinitrophenol, better known as DNP, is a yellow crystalline solid with a sweet, musty odor. It is a manufacture chemical that is not found in the environment. Buy DNP capsules online
2,4-Dinitrophenol (DNP) has many uses, 2,4-dinitrophenol is best known as a dangerous but effective fat burner and weight loss agent in the underground bodybuilding supplement industry.
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Stanford University researchers, originally used as a lighter for TNT and as a pesticide, found that DNP caused weight loss in 1933. The late bodybuilding pioneer Dan Duchaine wrote about DNP to reduce fat weight loss and DNP was use in underground bodybuilding for fat and fat. weight loss for decades. Compared to other thermogenic, fat reducing and weight loss agents such as the Epederin / Caffeine / Aspirin (ECA) stack would increase the user’s metabolism by 3% or the Clenbuterol / Cytomel T-3 stack, which would increase metabolism between 5 and 10% , DNP increased metabolism by up to 50% relatively controlled, making DNP a seemingly miraculous supplement. While clen / t-3, ECA and others significantly increased body temperature, DNP increased core temperature by 2 to 4 degrees F. Buy DNP online
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The main problem with DNP is its serious side effects. Exercise during a DNP cycle should be limited to workouts. DNP has not caused cancer, but death is a possibility if DNP increases the user’s body temperature too much, as there is no limit to how much DNP can heat the user’s body. The lethal dose of DNP is only 4 times the effective dose for weight and fat loss. DNP is not an appetite suppressant, so the user will be hungry and DNP users will especially crave carbohydrates due to the inefficiency of glucose. Some users may be allergic, and less than 1% of women who used DNP in the 1930s for fat reduction and weight loss developed cataracts which led to the FDA banning 2,4-dinitrophenol DNP as a weight loss drug in 1938.
It has since been use off and on with control in and above the body building industry. DNP protesters point out that DNP is not an indulgent chemical. Understanding what the effects, risks and limitations of the substance are before attempting to purchase and use DNP further boosts their hopes of discouraging potential DNP users, but the effectiveness of DNP in aiding fat reduction and ultimately weight loss is hard to deny. One danger is the fact that DNP has a cumulative effect with a half-life of 36 hours. DNP takes up to 48 hours to remove itself from a user’s system. Many bodybuilders adapt the “more is better” theory to DNP use, severely increasing the risk of harmful side effects and possibly death.
Weight loss with DNP – Scientifically Speaking
DNP achieves the astonishing increase in metabolic rate by inhibiting the ATP synthase molecule F0F1, located in the inner wall of each mitochondria. Although electron transport still functions to pump hydrogen ions into the intermembrane space, DNP makes it impossible to couple the proton gradient to ATP production. As a result, ATP production is dramatically reduced and energy is wasted in the form of heat. This results in astonishing heat production; When using dinitrophenol, the athlete radiates so much heat that it is uncomfortable to stand near him.
Fortunately, this heat does not contribute entirely to the increase in body temperature and instead is emitted from the entire surface of the body, especially the head. As a result, adequate doses of DNP generally raise body temperature by about 1-1.5°C.
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This is good for the central nervous system and other delicate tissues. If the heat produced by ATP contributed more directly to body temperature, effective doses for fat loss would increase body temperature. However, overheating is a very real danger.
Under such conditions, much of the food we eat could not be used for ATP synthesis and we lose weight. However, it is very inhibitory and we may be producing very little ATP for the rest of our lives. The difference between weight loss and death is only a small change in dinitrophenol concentration, which makes the drug dangerous. Simply put, this means that when eating your normal diet, you will have between 20% and 40% reduction in calories.
Risks of using 2,4-dinitrophenol DNP for weight loss
Hearing all these wonderful things, you are probably wondering what the side effects and risks are. They are very good and help make DNP one of the most intolerable (albeit effective) drugs used in bodybuilding.
CONSUMPTION OF DNP FOR WEIGHT LOSS EFFECTS is NOT recommended in any way, but if you are exposed to it, experience any of these side effects and they are extremely bothersome, it is recommended to discontinue immediately and consult your doctor. possible. Do not attempt further exposure at that point.
Safe and effective dose of DNP
at least as safe as possible when using DNP for weight loss. The dose is highly individualize and most generalizations tend to collapse fairly quickly. As a result, no one will be tempted. Start at the lower end of the scale and see how you respond. Taking more than 300 mg at a time is not recommended. Getting the correct dose of DNP is fairly easy to do, although the importance of the correct dose cannot be underestimated. It is far better to sin a little than a lot, certainly in the case of the novice who does not know if they are allergic to the substance.
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As mentioned above, the dosage commonly used by bodybuilders and other reasonably lean people is 4 to 6 mg / kg bodyweight. This would mean that a 100 kg bodybuilder would consume between 400 and 600 mg per day. Experienced users usually consume up to 800 mg per day with relative safety. And beginners sometimes find that they enjoy 3-5 pounds of fat loss per week with as little as 200 mg per day. Therefore, a person weighing 200 pounds would weigh about 91 kg.
Therefore, 4 mg per kg of body weight would be the equivalent of 364 mg of DNP per day. Since DNP is available in 200 mg capsules, the user must take a limit twice a day to stay within the range. The lethal dose is only 32 mg / kg just 4 times the maximum effective dose of 800 mg / day. “More is better” is not true in this case. Heed the warning!
DNP should be given in 8 to 12 day cycles to prevent liver and kidney damage and allow muscles to recover. Bodybuilders generally look their best 48-96 hours after discontinuing use. A 10-day cycle of 400 mg per day (200 mg twice daily) would be a typical effective dose for a 225-pound man. This allows a total of two weeks from start to finish, with a 4-day recovery period. Positive results were observe with a lower dose, but conversely, better results were safely obtain with a higher dose. Positive results were observe in users taking 200 mg to 800 mg per day. Remember the formula of 4-6 mg / kg body weight.
As DNP has this inhibitory effect, glucose is also inhibited, leading to a diabetic effect due to glucose conversion without insulin, so you may have heard of people taking insulin with DNP. This will counteract the symptoms of lethargy and lack of energy due to DNP use.
Timeline of effects and symptoms of a DNP
DNP CYCLE day 1 – none; possibly carbohydrate cravings and/or elevated temperature.
DNP CYCLE Day 2 – T4-T3 conversion has started to decrease; possible lethargy Temperature should be high and heat radiation is evident.
DNP CYCLE Days 3-5 – Body temperature is increasing, with all the effects expected from DNP use. Also, water retention usually manifests itself here. Buy DNP capsules online
DNP CYCLE days 6-10 – definite water retention, along with other symptoms of use; user is more likely to feel fatter due to having “flatter” muscles (mainly as a result of glycogen depletion) and drinking water. Final dose of DNP taken on the evening of day 10. Buy DNP online.
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DNP CYCLE Days 11-12: DNP is clearing the system slowly. All symptoms are still present.
DNP CYCLE 13-14 days – the water should have run out or gotten there. Mild diuretics will speed up this process. The user will likely notice an increase in perceived cardiovascular and muscular endurance.
96 hours after the final dose – This is when someone tends to be at their best.
Learn more about DNP.
This product is design for research and laboratory purposes only. The product is not a medicine or dietary supplement.