Pharmaceutical-grade psychedelics
Toad Venom Psychedelics, Sonoran desert toad venom contains a psychoactive compound that can be ingested to induce a powerful psychedelic experience. Although illegal in the United States, this substance is growing in popularity and research on its active ingredient shows potential for treating depression. Experts warn to be aware of the environmental and safety concerns associated with frog venom.
Venom is generally considered a substance to be avoided, and frogs are not the most attractive creatures. So why ingest or smoke their venom? For the psychedelic experience, of course.
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The use of frog venom as a drug is not new: it was already used for various purposes in pre-Columbian cultures. It enjoyed a renaissance in the 1960s counterculture and is making a comeback today, with celebrities like Mike Tyson and Christina Haack praising its life-changing properties.
The active ingredient in the poison is 5-MeO-DMT, a psychedelic chemical. While it is possible to ingest frog venom by licking its back, it is more common to extract the venom and grind it into a powder before smoking it. Users report that smoking the poison induces a psychedelic high within 10 to 30 seconds, which distorts vision and hearing and can leave the user physically incapacitated for about 30 minutes.
Toad Venom Psychedelics , 5-MeO-DMT
According to the Addiction Center, some users describe this trip as “a sense of awareness, connection to a higher power and rebirth.” Users often report changes in mood and perception, and some even feel motivated to make major changes in their lives because of their newfound knowledge.
“Although the therapeutic benefit of frog venom is unlikely to be studied, several groups are investigating the therapeutic benefit of 5-MeO-DMT for indications such as treatment-resistant depression and drug addiction,” says behavioral pharmacologist Joseph Araujo, chief scientist and pharmacologist at Mindset Pharma, a biotechnology company dedicated to the exploration and development of low-cost
pharmaceutical-grade psychedelics.
Araujo notes that the rise in popularity of toad venom may be the “psychedelic renaissance” we are experiencing, which has increased discussion about the potential usefulness of these substances.
“Many patients are not finding relief with currently approved medications and are seeking help from unregulated or less regulated approaches,” Araujo says. “Together, this appears to have fueled interest in several psychedelics, including 5-MeO-DMT.”
Safety concerns
It is important to note that there is a lack of safety data. Because 5-MeO-DMT is potent, Araujo says, dangerous drug interactions are possible.
“In our studies, we found signs of serotonergic syndrome at high doses, which can lead to death in humans,” Araújo says.
Matt Glowiak, PhD, LPC, an advanced addiction and substance specialist, adds that 5-MeO-DMT is ranked as one of the top drugs in the United States.
“In high doses, people can become disoriented, nauseated and even pass out,” says Glowiack. “The hangover effect can last for days. In addition, for people with psychotic or other diagnosable mental and addictive disorders, the experience can be a trigger that worsens symptoms. Something beyond their ability to control. It can be frightening.”
Environmental impact
Another area of concern is the environmental impact of extracting poison from frogs. The Sonoran desert toad is found only in northern Mexico and the southwestern United States and is considered endangered in California and endangered in New Mexico.
Robert Anthony Villa, a researcher at the University of Arizona, has publicly intervened to protect this “exploitable” frog species. The Tucson Herpetological Society initiated the Sonoran Desert Toad Fund for research and conservation of the species. Some of their products say “Forget the Frogs!” and “Responsible Travel.”
Frogs do not need to be stressed to obtain 5-MeO-DMT.
However, being responsible does not necessarily mean giving up the psychedelic experience of 5-MeO-DMT. It’s important for people to realize that the compound can be synthesized, Araujo says.
“The effects will be the same, and you don’t need to stress frogs unnecessarily to get 5-MeO-DMT,” Araujo says.
Research proves it: a 2019 study from Johns Hopkins University found that the synthetic version of 5-MeO-DMT can also alleviate depression. Another 2019 study in Europe found that inhaling a single dose of 5-MeO-DMT induced feelings of increased life satisfaction and reduced feelings of anxiety, depression and PTSD.
While more research is needed on synthetic 5-MeO-DMT to determine its true benefits, the potential to reduce the drug’s environmental impact is incredibly valuable.
What it means for you
While frog venom can induce a mind-altering psychedelic experience, it has environmental and safety concerns and is not recommended for recreational use.
